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The primary efficacy endpoint during the first 2 years of treatment was change in International Prostate Symptom Score IPSS an 8-item instrument based on AUA-SI with an how much is avodart cost question on quality of life.not known cannot be estimated from the available data Allergic reactions including rash, pruritus, urticaria, localised oedema, and angioedema These sexual adverse events are associated with dutasteride treatment including monotherapy and combination with tamsulosin These adverse events may persist after treatment discontinuation.
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Dutasteride also increases risk of high-grade prostate cancer.Secondary efficacy endpoints after 4 avodart prices of treatment included time to clinical progression defined as a avodart price of: IPSS deterioration by 4 points, BPH-related events of AUR, incontinence, urinary tract infection UTI and renal insufficiency change in International Prostate Symptom Score IPSS maximum urine flow rate Qmax and prostate volume.
Results following 4 years of treatment are presented below: Baseline values are mean values and changes from baseline are adjusted mean changes.
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