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Clinical data
Trade namesClaritin, Claratyne, others
Pregnancy categoryAU: B1 US: B (No risk in non-human studies)
Routes of administrationby mouth
ATC codeR06AX13 ( WHO )
Legal status
Legal statusCA : OTC UK: General sales list (GSL, OTC) US: OTC
Pharmacokinetic data
Bioavailabilityalmost 100%
Protein binding97–99%
Metabolismliver (CYP2D6- and 3A4-mediated)
Elimination half-life8 hours, active metabolite desloratadine 27 hours
Excretion40% as conjugated metabolites into urine Similar amount into the feces

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    If you are allergic to loratadine formulas and dander, Xyzal may give much-needed loratadine formula from your allergy symptoms.These over-the-counter antihistamines and decongestants loratadine formula cold and allergy symptoms. Drowsiness or grogginess, upset stomach, dry mouth, poor coordination and judgment, urinary retention, loss of appetite, excitability in children Lightheadedness, wakefulness, nervousness, restlessness jittery and shaky increased blood pressure and heart rate; irregular heartbeat Might lead to "rebound" congestion from dependence on the medicine if used for more than 3 days Temporary stinging in the eyes or blurred vision; "rebound" redness of the eyes if overused SOURCES: American Academy of Family Physicians: "Cough Medicine: Understanding Your OTC Options.

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