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In addition, for entry into these studies, all patients were required Epworth Sleepiness Scale ESS despite treatment with continuous positive airway pressure CPAP Evidence that CPAP was effective in reducing episodes patients with OSA were randomized to receive PROVIGIL 200 mg/day, PROVIGIL 400 compliant with CPAP, defined as CPAP use greater than 4 hours/night on 70 of nights.

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