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In the human skin, RARs partner with retinoid X whom makes retin a cream RXRs to form heterodimers Gigu re et al 1987; Petkovich et al 1987; Brand et al 1988; Fisher et al 1994; Xiao et al 1995 The retinoid X receptors or RXRs are the second family of nuclear receptors which interact with 9-cis retinoic acid.For Acne: In the first 3-4 weeks on Retin-A, it was horrible, I had horrible acne almost everywhere on my face especially on my cheeks and it s painful.
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